The Best Gluten-Free Mississippi Meatloaf Recipe

Baked Mississippi Meatloaf is a delicious, comforting twist to a classic meatloaf, plus it’s made with corn meal making it gluten-free! There are no breadcrumbs used in this easy recipe. This recipe is inspired by the flavors of Mississippi Pot Roast. These flavors happen to be my favorite, making it gluten-free just makes it even better!

Mississippi Meatloaf mixes ground beef with buttery, rich flavors and zesty pepperoncini and ranch seasoning to give it a delicious twist.

What you’ll love about Mississippi Meatloaf:

• Easy to make gluten-free!
• Packed with flavor.
• Ready in less than an hour, makes a great weeknight dinner.
• Leftovers are just as good!
• Pantry ingredients!

Ingredients for Mississippi Meatloaf:

• Ground Beef (80/20)
• Corn Meal
• Chicken Broth
• Gluten-Free Worcestershire Sauce
• Ranch Seasoning
• Pepperoncini
• Whole Egg
• Butter

Step-by-Step Instructions:

1. Preheat the oven to 350 degrees F.
2. Lightly grease an 8-inch cake pan and set aside.
3. In a large mixing bowl, combine the ground beef, corn meal, chicken broth, Worcestershire sauce, ranch seasoning, chopped pepperoncini, and egg.
4. Mix until all ingredients are well combined.
5. Shape into a meatloaf and place in the cake pan.
6. Top with the sliced butter and pepperoncini.
7. Bake at 350 degrees F or until the internal temperature reaches at least 165 degrees F.
8. Let the meatloaf rest for 5 minutes before serving.

Tips for Making Gluten-Free Mississippi Meatloaf Recipe:

The ingredients in this meatloaf are naturally gluten-free; however, not all brands are equal. Be sure to check all ingredients before using to be sure there is no cross-contamination.

• Use an 8-inch cake pan to hold in the moisture.
• Do not overmix.
• Add the slices of butter right on top.
• Let the meatloaf rest before serving to allow the juices to redistrubute.
• Perfect to serve with Mashed Potatoes!
• Use 80/20 ground beef, 90/10 can be used but it will result in a drier meatloaf.

Best Baking Time for Mississippi Meatloaf Recipe:

This recipe will bake at 350 degrees F for 40-50 minutes or until the internal temperature reaches at least 165 degrees F. This is best monitored with a meat thermometer.

How to store leftover Meatloaf:

Once fully cooled, store in an airtight container in the fridge for up to 4 days. When ready to reheat, heat in the microwave on a microwave-safe plate for 1-2 minutes or until warm through.

If you love this Gluten-Free Mississippi Meatloaf, but want to cook it even faster, try the Air Fryer Version or this Tangy Meatloaf Recipe!